PO-05-060 SUBCUTANEOUS VERSUS TRANSVENOUS IMPLANTABLE CARDIOVERTER DEFIBRILLATOR THERAPY: A META-ANALYSIS

نویسندگان

چکیده

Subcutaneous implantable cardioverter defibrillators (S-ICD) are safe and effective for the prevention of sudden cardiac death. To compare safety efficacy S-ICD with transvenous (TV) ICD. Database search was performed all RCTs and/or propensity score-matched (PSM) studies comparing against TV-ICD. The primary outcome lead-related complications. Secondary outcomes included device-related complications, appropriate inappropriate shocks, all-cause mortality, deaths. We 6 (2 4 PSM) a total 2,890 patients (1,446 vs 1,444 TV-ICD). mean age 54±15 years, 23% were female, 47% ischemic cardiomyopathy, 22% had atrial fibrillation. EF 37±15% 75% ICD prevention. Compared TV-ICD, associated significant reduction in complications (OR=0.13; 95% CI=0.05 – 0.36; p<0.01; NNT=23) (OR=0.56; CI=0.32-0.99; p=0.05; NNT=34). There no difference shocks (OR=1.16; CI=0.70-1.70; p=0.44). Individual trials’ OR shock ranged 0.48 2.38 (no individual trial statistically this endpoint), likely due to heterogeneity device tachytherapy programming. differences between groups regards or deaths (p>0.05). Among ICD, significantly lower rates lead- compared mortality.

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ژورنال

عنوان ژورنال: Heart Rhythm

سال: 2023

ISSN: ['1556-3871', '1547-5271']

DOI: https://doi.org/10.1016/j.hrthm.2023.03.1488